ALDH2: the alcohol flush
Your genotype · G/A → Reduced clearance, flush-prone
EU-sovereign · DNA re-analysis · made in Finland
Your genome doesn't change.
What we know about it does.
Aimosti re-analyses a DNA file you already own, a sequenced genome or a 23andMe-style chip export, against current clinical and research databases. When the evidence shifts, we re-read your file and flag what changed.
Drop your DNA file here
or click to choose · a genotyping-array export from 23andMe, AncestryDNA, MyHeritage, FamilyTreeDNA, LivingDNA, or a VCF/gVCF from Nebula, Dante, Sequencing.com
Read on your device, not ours. Your file is never uploaded and no account is needed. We are a genomics company telling you not to send us your genome yet, and that is deliberate. Security & your data →
Reading on your device…
That's . We can build your report from it.
What it can tell you
What it can't
A chip reads a fixed set of common spots, so the rare-variant panels need a sequenced genome. We tell you this now rather than after you have paid.
One-time, yours to keep. Your file is still on your device: you upload it after checkout, over an encrypted connection, to storage in Finland.
That's : aligned reads.
This is exactly what the Deep Read pharmacogenomic panel needs: 29 targets read at base level, including the CYP2D6 star-alleles a normal VCF cannot reliably call. The standard report is built from a VCF/gVCF, so aligned reads sit alongside one rather than replacing it.
Deep Read needs standard-depth reads. A low-pass file, MyHeritage's own sequencing download among them, is read about twice over rather than thirty times, which is too thin to call these genes from. We measure the depth and stop rather than guess.
A CRAM also needs the exact reference assembly it was compressed against, not merely the same genome build. We hold the common ones and check yours before taking any money, so an assembly we cannot read is refused rather than charged for.
Nothing was uploaded, and you have not paid anything. We would rather turn a file away here than sell you a report it cannot support.
This check ran on your device from your file's header. We confirm the full file after upload, and never charge for a report we cannot build.
From €49 for a genotyping-array file (23andMe, AncestryDNA, MyHeritage, FamilyTreeDNA, LivingDNA), or €89 for whole-genome. One-time, yours to keep.
We keep your report current. Own every report forever. €29/yr keeps it updating. Stop anytime and you keep the last one. Never rented back to you.
Your data stays in Finland. Encrypted in transit, never sold, deleted on demand.
Restated from
ClinVar·ACMG SF·CPIC·GWAS Catalog·gnomAD·PhyloTree
We restate the science. We never originate it.
What Aimosti does
- Re-analyses variant data you already own (a chip export or a whole genome)
- Restates ClinVar, ACMG SF, CPIC, GWAS Catalog & PhyloTree, pinned to a version
- Shows evidence and effect on two separate axes, never one score
- Names the gaps: what a variant file cannot tell you
- Re-runs as the databases improve (subscription)
What Aimosti never does
- Take a sample, sequence, test, or diagnose
- Invent a gene or variant association on our own authority
- Collapse weak evidence into a confident-looking number
- Sell, share, or mine your data
- Report MTHFR or APOE as a clinical finding (we explain why)
Modules
Everything our panels read from a variant file.
Each module is anchored to an authoritative, version-pinned source. The speculative modules are walled off from the clinical ones, so curiosity never wears the authority of settled science.
ClinVar / ACMG SF v3.3
Clinical findings
Pathogenic / likely-pathogenic variants in an established actionable-gene panel, framed as personal risk, never a verdict.
ACMG Tier 3 + ACOG carrier panel
Carrier status
A recessive-lens look at carrier variants in your file, for family planning, with the un-callable conditions named.
CPIC guidelines
Pharmacogenomics
How your genotype may affect specific medicines, restating CPIC, to discuss with a prescriber.
GWAS Catalog
Traits
Benign, well-replicated, genome-wide-significant traits that clear a strict evidence gate. No SNPedia folklore.
PhyloTree
Ancestry · maternal & paternal
Your deep maternal and paternal lines as global haplogroups, one thread of your tree, never a "percent ancestry" figure.
below the firewalllabelled exploratory, never clinical
Expanded · exploratoryEmerging research
Frontier
Dozens of readings from the interesting edge of the science: alcohol-flush and caffeine metabolism, the natural short-sleeper genes, longevity curios, and the over-hyped classics we keep in to set the record straight (the “warrior gene”, the serotonin-transporter “depression gene”). Each one is labelled by how much it weighs.
Just for funSpeculative · curiosity only
The Fringe
The playful gene-quirks people love to look up (why coriander can taste of soap, red hair, spicy-food tolerance, even the genetics of rage at chewing sounds), labelled, bluntly, as for curiosity only.
For the biohackers. Straight about the uncertainty.
Everyone else either hides the speculative stuff or sells it as gospel. We show dozens of the variants you actually want to see, each wearing a blunt evidence tier, from replicated down to contested. The honesty is the product.
The report shows its working.
Every finding shows its variant, your genotype, the source's own confidence, and how common it is, with plain-language explainers a tap away. No gamified scores, no dark patterns.
Factor V Leiden thrombophilia
＋ NEW ClinVar reclassified a variant in your file to Likely pathogenic.
~ UPDATED A Frontier association gained a replication cohort.
· STABLE Everything else unchanged since your last report.
Your genome can tell more.
The science isn't settled.
Databases improve every month. Keep just your small normalised variant file and its ancestry marker extract with us, never raw reads, and we silently re-match them as the literature moves, then tell you plainly what changed. Withdraw any time; your last report is always yours.
≈ €29 / year · raw reads never retained
Your most personal data, governed like it matters.
- EU ONLYStored and processed in FinlandStored in servers in Helsinki. Your genome never leaves the EU.
- ART. 9Explicit, revocable consentGenetic data is special-category under GDPR. One explicit consent processes your file and produces your report; research and marketing stay separate and optional, every choice withdrawable, auditable, and versioned.
- CRYPTOEncrypted, never soldEncrypted in transit. We don't sell, share, or mine your data, ever.
- DELETEDeleted on demandRaw reads are purged after analysis. Subscribers keep a small normalised variant file and its ancestry marker extract, and only if they ask us to. Delete everything with one request.
Pay once. The report is yours, and you can keep it current if you choose.
Pick where to start. Every report is a one-time purchase you own forever. To keep it current as the science moves, add the re-analysis subscription for €29/yr. Compare plans →
Genotyping chip
Chip report
€49 one-time
For 23andMe, AncestryDNA, MyHeritage, FamilyTreeDNA, LivingDNA and similar genotyping-array exports: everything your chip can call, fully attributed. Carrier status and the full clinical panel need whole-genome data. MyHeritage kits sold since October 2025 may be sequenced rather than typed on an array, so check which file you have.
- Clinical findings your array covers
- Pharmacogenomics for the genes your chip typed and resolved
- Traits, ancestry & the Frontier module
- Plain-language explainers & PDF
Grow into it: upgrade to the full WGS report for €40 whenever you’re ready.
Most complete report
Full report (WGS)
€89 one-time
Every module over your whole-genome file: the deepest read of the genome you already own.
- Clinical, carrier, PGx, traits, ancestry
- Frontier exploratory module
- Plain-language explainers & PDF
- Pinned, attributed sources
The full clinical-findings panel and carrier status live here. A chip file cannot give you either.
From your aligned reads
Deep Read
€109 one-time
A 29-target pharmacogenomic panel (CYP2D6 + 28 more) from your aligned reads (the BAM or CRAM from your provider), with a per-gene callability map of exactly what we examined.
- 29-target pharmacogenomic panel
- CYP2D6 star-allele resolution
- Per-gene callability, measured
- Reads deleted immediately after
Prepay Deep Read with the WGS bundle to save.
The cheaper option, and what it costs later
Promethease and Genetic Genie read the same public databases we do. The difference is time. They hand you a report frozen on the day you run it, read from the few hundred thousand positions a genotyping chip types. We read your whole genome where you have it, attribute every finding to the guideline it came from, and can re-read your file as those guidelines change. Your report is a one-off purchase and stays yours. Keeping it current as the guidelines move is the optional re-analysis subscription, and you can start or stop that whenever you like.
Named services are described from their public product pages; features change and we don't speak for them. Three years later, that report still says exactly what it said on the day you ran it.
Common questions
Do you sequence my DNA?
No. Aimosti never takes a sample or sequences anything. You bring whole-genome data you already had produced; we re-analyse the variant file.
Is this a medical test or diagnosis?
No. Every finding is a literature match against public databases: information to discuss with a clinician and confirm with a validated gene test. It is never a diagnosis or medical advice.
What files do you accept?
A whole-genome gVCF gives the most complete report: it records which regions your sequencing covered, so "not found" can mean "examined and clear" rather than merely absent. A plain VCF also gives the full report, read as variant-only. Nebula Genomics, Dante Labs, Sequencing.com and the like are good to go. Several of them, Nebula, Gencove and Dante among them, only ship a variant-only VCF; that still gives the full report, so upload what you have. Check which depth you bought, though: a whole-genome product can be sold at 1x or 2x as well as at 30x. A low-pass genome is imputed against a reference panel rather than read directly, which is good for ancestry, traits and pharmacogenomics and cannot carry the clinical-findings and carrier panels, so it is the €49 report rather than the €89 one. Genotyping-array raw data from 23andMe, AncestryDNA, MyHeritage, FamilyTreeDNA or LivingDNA works too, for a lighter report (traits, pharmacogenomics and ancestry); clinical findings and carrier status need a sequenced genome. MyHeritage kits sold since October 2025 are sequenced rather than typed on a chip, and the raw-data export they hand you still works here.
Where does my data live?
Stored in Finland (Helsinki), never leaving the EU, never sold or mined, deleted on demand. Security & your data →
The genome you already own has more to say.
One living report, many modules. Read in Finland, attributed to the source, yours to keep.
Get your report · €89