Question 1

Do you sequence my DNA?

Accepted Answer

No. Aimosti never takes a sample or sequences anything. You bring DNA data you already had produced: a sequenced genome from a provider like Nebula, Dante or Sequencing.com, or a consumer chip export. We re-analyse the variant file against current databases.

Question 2

Is this a medical test or a diagnosis?

Accepted Answer

No. Every finding is a literature match against public databases: information to discuss with a clinician and confirm with a validated gene test. It is never a diagnosis or medical advice.

Question 3

What files do you accept?

Accepted Answer

A whole-genome gVCF gives the most complete report: it records which regions your sequencing covered, so "not found" can mean "examined and clear" rather than merely absent. A plain VCF gives the full report too, read as variant-only, where an absence could be the reference allele or an uncovered position. Several providers, Nebula, Gencove and Dante among them, only ship a variant-only VCF, so upload what you have. A whole-genome product can be sold at 1x or 2x as well as at 30x, so check which depth you bought. A low-pass genome is a different product rather than a broken one: at that depth the genotypes are worked out against a reference panel instead of read directly, which is what makes it good for ancestry, traits and pharmacogenomics. What it cannot carry is the clinical-findings and carrier panels, because those turn on rare variants and a reference panel is weakest exactly there. So it is the €19 report rather than the €39 one, and we would rather read your file at the right price than turn you away. Genotyping-array raw data from 23andMe, AncestryDNA, MyHeritage, FamilyTreeDNA or LivingDNA works as well, sent as the .zip exactly as they made it: you get traits, ancestry and per-variant-transparent pharmacogenomics. MyHeritage kits sold since October 2025 are sequenced rather than typed on a chip; they still hand you a raw-data export in the same format and it works here, with genotypes worked out from the sequencing rather than read straight off an array, and no Y chromosome in the file. The full clinical-findings panel and carrier status need a sequenced genome, though a chip can still surface a few specific single-variant findings, such as Factor V Leiden and Prothrombin G20210A, shown for that variant only. An aligned-reads file (BAM/CRAM) adds the Deep Read pharmacogenomic panel, as long as it was sequenced at standard depth; we measure the depth and stop rather than guess on a low-pass file.

Question 4

Which reference build do you need, GRCh38 or GRCh37?

Accepted Answer

Both work. Some providers, Dante among them, still deliver GRCh37. On a GRCh37 file Deep Read runs in full, CYP2D6 copy number and the 29-target pharmacogene panel included; the wider clinical coverage map and the recurrent-deletion screen are GRCh38-only, and we report those as not measured rather than estimating them. You can check which build your own file carries on this device, before paying.

Question 5

What are the Frontier and Fringe modules?

Accepted Answer

Two optional, clearly-firewalled sections for emerging and exploratory research: the variants biohackers actually ask about, which is alcohol-flush and caffeine metabolism, the natural short-sleeper genes, longevity curios, and the over-hyped classics we keep in to set the record straight. The lighter Fringe collects the fun gene-quirks (cilantro-soap, red hair, spicy-food tolerance, misophonia). Each entry is labelled by evidence strength, contested and over-hyped included. For curiosity, never medical.

Question 6

Where does my data live?

Accepted Answer

Stored in Finland (Helsinki), never leaving the EU, never sold or mined, deleted on demand.

Question 7

What does it cost?

Accepted Answer

€39 once for the full report. An optional €79 Deep Read add-on if you have aligned reads (BAM/CRAM): CYP2D6 copy number, per-gene callability measured from depth, two recurrent deletions and typed HLA-DQ, alongside the full 29-target pharmacogene panel. And an optional €29/yr re-analysis subscription.

Question 8

Can I get a refund?

Accepted Answer

Yes, in full, if you withdraw before your report is generated, or if we genuinely cannot produce your report. Once your personalised report has been generated and the right of withdrawal validly waived, no further refund is given except where mandatory law requires it. Valid refunds go back to the original payment method, normally within 14 days.

Question 9

What is the re-analysis subscription?

Accepted Answer

Databases improve constantly. If you opt in, we keep your small normalised variant file and the ancestry marker extract read from it, never raw reads, and silently re-match them as the science moves, then tell you what changed. Cancel any time; your last report is always yours.

Question 10

Is this a subscription trap?

Accepted Answer

No. You pay once for the report and own it forever. The €29/yr only keeps it updating as the science moves; cancel anytime and you keep your last report. We never hold your report hostage.

Question 11

Can I delete everything?

Accepted Answer

Yes, at any time, with one request or by deleting your account.

Question 12

Is my data used to train AI?

Accepted Answer

No. We sell reports. We have never sold data, and we do not train models on yours.

Question 13

What happens to my data if Aimosti shuts down?

Accepted Answer

Your data is never an asset we would sell. That's the whole lesson of the 23andMe bankruptcy. If we ever wind the service down, the commitment is export-first, then deletion: you can export what's yours, and then it is permanently deleted, never transferred to a buyer.

Question 14

Can my insurer or employer get this?

Accepted Answer

Not from us. We never sell or share your data, and your report lives behind your account, in the EU, deletable on demand. (Genetic-discrimination protections vary by country; the US has GINA, and the EU/Finland has its own safeguards, but the simplest protection is that your data never leaves your control to begin with.)

Question 15

Do you offer CYP2D6, HLA or other specialised genes?

Accepted Answer

The Deep Read add-on (€79) reads what only aligned reads (BAM/CRAM) can answer: CYP2D6 copy number, a measured per-gene callability map, two recurrent deletions and typed HLA-DQ, alongside the full 29-target pharmacogene panel (CYP2D6, CYP2C19, TPMT, DPYD, SLCO1B1, NUDT15 and more). CYP2D6 is the flagship example: its gene structure (duplications, deletions, pseudogene interference) means a variant file cannot see how many copies you carry. From a gVCF, the full report itself now resolves 25 pharmacogenes to CPIC star alleles and states, gene by gene, how many defining positions your file examined. Deep Read also types HLA-DQA1 and HLA-DQB1 from the same reads, which is what a celiac rule-out needs. The two HLA-B drug alleles in every report, B*57:01 for abacavir and B*15:02 for carbamazepine, are inferred from a tag variant rather than typed, and the card says so. We'd rather say "not from this file" than imply a result we can't stand behind.

Question 16

How long does a report take?

Accepted Answer

Most whole-genome reports on GRCh38 are ready 5–15 minutes after the upload finishes. A GRCh37 file is lifted to GRCh38 first, and a large gVCF on that build can take a couple of hours. Deep Read takes about half an hour once the reads are in. We email you when it is done, so there is no need to keep the tab open.

Frequently asked.

Clinical findings

Carrier status

Pharmacogenomics

Single-gene reads

Traits

Polygenic risk scores

Deep ancestry

Frontier

The Fringe

Deep Read: 29-target pharmacogenomic panel Deep Read add-on

Recurrent deletion calls Deep Read add-on