aimosti

You already sequenced your genome. Nobody read it to you.

If you bought a 30x genome from Nebula, Dante Labs, Sequencing.com or Gencove, you were handed a folder of files and left to work it out. The sequencing was the hard part and it is already done. Aimosti reads the files you own and gives you the report they did not come with.

Your variant file says what you have. It does not say what was read.

Nebula, Dante and Gencove all hand you a variant-only VCF. It lists the positions where you differ from the reference, and says nothing at all about the rest. So when something is absent from that file, there are two possible reasons and the file cannot tell them apart: the position was read and you are clear, or the position was never read.

Any service working from that file alone has the same problem, this one included. We say so on the file check, before anyone pays.

Your reads settle it, across the whole panel.

The other file in that folder is the aligned reads, your BAM or CRAM. It is the record of what the sequencer actually saw, position by position. We measure depth across every region of the report panel and count the bases covered at 10x or better, so each gene comes back examined, partly examined, or not measured.

That is the whole panel your report is built from, not a sample of it. It is the difference between a report that says nothing was found and a report that says where it looked.

Your reads are deleted when the run finishes, whether it succeeded or failed. Everything stays in Finland.

And two things a variant file cannot give you at any price.

  • CYP2D6Star alleles, called from the readsThe gene comes in duplications, deletions and hybrids with its neighbouring pseudogene. That is structure rather than a list of positions, so a variant file cannot resolve it. It is the most prescribed-against pharmacogene there is, and it sits inside the 29-target panel.
  • DELWhole-gene deletions, called from depthA deletion shows up in a variant file as an absence of calls, which is indistinguishable from a region nobody looked at. Measured against read depth it is simply visible.

Both are on the Deep Read panel, which is what your reads buy. The full list of what each kind of file covers is on what we analyse.

What we will not do with your file.

  • We will not read a low-pass genome as a deep one. A 1x or 2x file is read about twice over rather than thirty times, which is too thin to call these genes from. We measure the depth and stop rather than guess, before the run is charged for.
  • We will not decode a CRAM against the wrong assembly. A CRAM stores your reads as differences from the exact assembly it was compressed against, so it cannot be read back without that same one. We check yours before taking any money.
  • Your BAM alone is not the whole report. The clinical, carrier and ancestry panels are built from a variant file. Your reads add the pharmacogenomic panel and the coverage proof on top. Providers who sequence you generally give you both files, which is what the bundle at €169 covers.

Check the file you have.

Drop it below. It is read inside this page, on your own device: nothing is uploaded, and you do not need an account to find out what is in it.

Get both · €169 See a sample report

The whole-genome report plus the Deep Read panel, prepaid together, against a list price of €198. Deep Read on its own, added to a report you already bought, is €109.