health

Lipoprotein(a): a cardiovascular risk factor with a real gap

Lp(a) is a major inherited heart-disease risk most people have never had measured. What can DNA say?

What the science says

Lipoprotein(a) levels are largely set by genetics at the LPA locus and high levels raise cardiovascular risk. DNA can carry tag variants associated with elevated Lp(a), but the gene is complex, and a genetic proxy is not the same as a blood measurement of the protein itself.

What Aimosti would show you

Aimosti restates the association for the tag variants present in your file, framed as a proxy that can flag likely-elevated Lp(a) and point you toward a confirmatory blood test, with evidence and effect kept separate, never a single risk number.

What we won't claim

This is an asymmetric, tag-SNP proxy: a positive tag suggests elevated Lp(a), but absence of the tag is not proof your Lp(a) is low. We won't read a clear genome as reassurance, won't replace the blood test, and won't give a personal risk figure.

Covered in: Lp(a). Restated from: GWAS Catalog.