traits

Are you a fast or slow caffeine metaboliser?

A common variant near CYP1A2 tracks how fast your liver clears caffeine. Sleep, tolerance and dose move the same needle, which is why one variant only takes you so far.

What the science says

A common variant near the CYP1A2 gene is associated, in well-replicated studies, with how quickly the liver clears caffeine. It is one well-studied input among many: sleep, tolerance, dose and other genes all matter.

What Aimosti would show you

Aimosti reads the CYP1A2 lead variant from the DNA file you already own, a 23andMe or Ancestry export included, and restates the GWAS Catalog association on two separate axes (how strong the evidence is, and how large the effect is), never collapsed into a single "score".

What we won't claim

We won't tell you how much coffee to drink, call this a diagnosis, or pretend one variant decides your caffeine response. It's one well-replicated input, framed as such.

Covered in: Traits. Restated from: GWAS Catalog.